|
KMID : 1101020190440010001
|
|
Journal of Oral Medicine and Pain
2019 Volume.44 No. 1 p.1 ~ p.10
|
|
|
Evaluation of Clinically Effective Doses of Triamcinolone Acetonide for Intralesional Injection in Oral Lichen Planus
|
|
Park Su-Hyeon
Lee Hae-Ohk
Ju Hye-Min
Lee Ji-Yeon
Jeon Hye-Mi
Ok Soo-Min
Ahn Yong-Woo
Jeong Sung-Hee
|
|
|
Abstract
|
|
|
Purpose: The aim of this study was to evaluate the optimal doses of intralesional triamcinolone acetonide (TA) in the treatment of oral lichen planus (OLP).
Methods: A randomized clinical trial was performed. Sixty-two lesions of OLP were received 12 mg (group A) or 20 mg (group B) of TA intralesionally weekly for 2 weeks. Subjective symptoms, lesion size, favorable conversion of clinical subtypes, and clinical response were evaluated at weeks 0, 1, 2, and 4.
Results: After two consecutive injections of TA, group B showed significant reduction in burning sensation and reticular area (p<0.01). Favorable conversion and complete response were greater in group B. Mild oral candidiasis was developed in group B (10.7%).
Conclusions: A 20-mg injection of TA was much more effective compared with 12-mg injection of TA in the treatment of OLP.
|
|
|
KEYWORD
|
|
|
Intralesional injections, Oral lichen planus, Triamcinolone acetonide
|
|
|
FullTexts / Linksout information
|
|
 
|
|
|
Listed journal information
|
|
|